Patients with the following conditions and/or taking the following medications may be at increased risk for acute phosphate nephropathy:

• Decreased intravascular volume (due to congestive heart failure, cirrhosis, or nephrotic syndrome)
• Acute or chronic kidney disease
• Advanced age (OSP-associated hyperphosphatemia may be more severe in individuals ages 57 years and above 3)
• Medications that affect renal perfusion or renal function such as diuretics, ACE inhibitors, ARBs, and possibly NSAIDs. more